Gastric
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Fibroblast-derived Spondin-2 promotes dysplastic transition in metaplastic gastric epithelial cells
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Fibroblasts are increasingly recognized as active drivers of early gastric carcinogenesis, yet the specific fibroblast-derived factors that promote the ...

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A Rare and Reversible Cause of Gastric Wall Thickening and Severe Anemia
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Question: A 53-year-old unemployed woman presented with a 3-week history of epigastric dull pain, fatigue, and weight loss. The patient reported a 3-week ...

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Refractory Gastric Ulceration
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Question: A 58-year-old man was referred to our unit by another hospital for consideration of performing a vagotomy to treat multiple gastric ulcers that ...

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A Giant Gastric Ulcer: Not What It Seems
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Question: A 66-year-old man presented with a 2-week history of intermittent epigastric pain. His medical history was notable for hypertension treated with ...

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10-Year Follow-Up After Endoscopic Submucosal Dissection for Clinical T1a Undifferentiated-Type Early Gastric Cancer ≤2 cm Without Ulceration in a Nonrandomized, Single-Arm Confirmatory Trial (JCOG1009/1010)
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Endoscopic submucosal dissection (ESD) is an organ-preserving approach used for early gastric cancer (EGC).1 JCOG1009/1010, a multicenter, single-arm, ...

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SRY-Box 9–Driven Spasmolytic Polypeptide-Expressing Metaplasia Cell Lineage Plasticity Is a Potential Therapeutic Target That Mitigates Risk of Metaplastic Progression to Gastric Cancer
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SRY-box 9 (SOX9) is a molecular regulator that plays an essential role in cell identity changes in response to stomach injury, which further drives stomach ...

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Serotonergic signaling in gastric physiology and motility disorders
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Serotonin (5-hydroxytryptamine; 5-HT) is a key regulator of gastrointestinal function and exerts its effects through a diversity of 5-HT receptors. In the ...

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Methodological Considerations on Central Pathology Review in Artificial Intelligence-Assisted Gastric Neoplasm Detection
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Methodological Considerations on Central Pathology Review in Artificial Intelligence-Assisted Gastric Neoplasm Detection

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