With the rising prevalence of inflammatory bowel disease (IBD), preventing new-onset disease becomes a priority. The PIONIR (Preventing IBD ONset in ...
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October 14, 2026 4 min read ...
Excessive accumulation of extracellular matrix (ECM) derived from human intestinal myofibroblasts (HIMF) drives the significant clinical problem of ...
In short, Crohn’s disease causes chronic, deep inflammation throughout the digestive tract. Treatment focuses on managing symptoms, reducing ...
Finding the best Crohn’s disease treatment means creating a plan that’s tailored to your unique symptoms, health profile, and lifestyle. No ...
August 19, 2026 4 min read ...
Intestinal fibrosis remains a debilitating complication of Crohn’s disease (CD). Canonical WNT signaling and WNT1 inducible signaling pathway protein ...
This study identifies an intestinal marker, glutathione peroxidase 4 (GPX4), that predicts Crohn’s disease recurrence after surgery and demonstrates it ...
We read with great interest the study by Gettler et al,1 which provides a comprehensive transcriptomic analysis of postoperative ileal recurrence in Crohn’s ...
Dysregulation of the interleukin (IL) 23–T helper 17 cell axis has emerged as a central driver of disease pathogenesis in patients with Crohn’s disease ...