{"id":326391,"date":"2025-12-01T17:12:43","date_gmt":"2025-12-01T17:12:43","guid":{"rendered":"https:\/\/peraltafinancing.com\/alternative-medicine\/new-information-on-elderberry-toxicity\/"},"modified":"2025-12-01T17:12:43","modified_gmt":"2025-12-01T17:12:43","slug":"new-information-on-elderberry-toxicity","status":"publish","type":"post","link":"https:\/\/fivemor.com\/?p=326391","title":{"rendered":"New Information on Elderberry Toxicity"},"content":{"rendered":"


\n<\/p>\n

\n

New Information on Elderberry Toxicity
<\/h2>\n

from the November\/December 2019 issue – The Essential Herbal
by Rebekah Bailey<\/p>\n

<\/a><\/div>\n

Writing this
\nparticular article proved to be one of my more interesting writing
\nexperiences.\u00a0 <\/span>I had completed and
\nsubmitted it, only to have a series of events unfold in the following couple of
\ndays which required Tina and me to discuss a re-write.\u00a0 <\/span>In a serendipitous turn of events, only hours
\nafter reviewing my article, Tina was approached by an elderberry farmer who
\nmentioned new research being conducted on elderberry toxicity.\u00a0 <\/span>As a result, I was able to run down and
\ninterview Andy Thomas, a research professor with the University of Missouri
\nSouthwest Center. He shared with me details of an elderberry toxicity research
\nproject, due to be published in the coming months. I will begin with the
\ncurrently accepted information on elderberry toxicity, and then follow up with
\nwhat I learned from Thomas.<\/span><\/p>\n

Conventional
\nwisdom regarding elderberries has been they are toxic when raw, and that the
\ncyanide producing compound in them is neutralized with heat.\u00a0 Elderberry
\nbranches, stems, leaves, and seeds contain potential cyanide in the form
\nof\u00a0cyanogenic glycosides. When ingested, these glycosides react with an
\nenzyme, beta-glucosidase, and hydrolyze, releasing hydrogen cyanide.
\nElderberries aren’t the only food containing cyanogenic glycosides: Lima beans,
\nflax seed, almonds, apple seeds, cherry and plum pits, apricot and peach pits,
\ncassava (the source of tapioca), spinach, peas, soy, and bamboo shoots.\u00a0 <\/span>However, I don’t see anyone losing sleep
\nover eating spinach and lima beans … ummm, well, maybe if you don’t like
\nthose vegetables.<\/span><\/p>\n

<\/a><\/div>\n

Exposure to small
\namounts of cyanide can cause dizziness, headache, nausea, vomiting, rapid
\nbreathing, and rapid heart rate. Exposure to larger amounts can cause
\nconvulsions, loss of consciousness, low blood pressure, and respiratory failure.
\nHow much ingested cyanide is toxic to human beings? Well I couldn’t find an
\nexact number, but one source cited 98 mg in one day (and stated the lowest
\ndocumented lethal dose as 37.8 mg), and the John Hopkins Center for Health
\nSecurity cites 100-200 mg when ingested as sodium or potassium cyanide.\u00a0
\nAnother source cited “0.5-3.5 mg\/kg bw. Approximately 50-60 mg of free
\ncyanide constitutes a lethal dose for an adult man.”\u00a0 <\/span>The human body is able to clear small amounts
\nof cyanide through the liver involving a molecule called thiosulfate, and if
\nenough tiosulfate is not present, then cyanide poisoning occurs.\u00a0 Taking
\nthis into account, it stands to reason that poisoning will vary from person to
\nperson, depending on body weight, fasting\/non-fasting, and individual metabolic
\nfactors. <\/span><\/p>\n

Having a general
\nidea of how much cyanide is lethal, the next question is how much cyanide can
\nyou find in elderberry? I could only find a couple of sources, which both
\nstated 3mg per 100 g of fresh berries, and up to 17mg per 100 g of fresh
\nleaves.\u00a0 <\/span>However, when I followed up with
\nboth articles’ source material, Assessment Report on Sambucus nigra L., fructus
\nby the European Medicines Agency, I could find no such numbers.\u00a0 <\/span>What the report did state was that
\ninformation regarding the level of cyanogenic glycosides in the fruits and seed
\nwas not available.\u00a0 <\/span>Of the two sources I
\nfound, one came to the conclusion that it\u2019s inconclusive just what the
\nconcentration of cyanogenic glycosides found in the berries and flowers.\u00a0 <\/span>If you were to go by the amount of 3 mg, then
\nit would take eating approximately 3 pounds of raw elderberries to get a toxic
\ndose of cyanide.<\/span><\/p>\n

Here is where the
\nnew Missouri University elderberry study becomes
\nrelevant<\/b>.\u00a0 <\/span>The University, working in
\nconjunction with several state agencies and farmers, have been exploring
\nelderberry as a commercial crop. A range of different studies have been
\nconducted and written about, the most recent focusing on the toxicity issue. <\/span><\/p>\n

The study focused
\non American Elderberry (Sambucus Canadensis), which is a different species than
\nthe European Elderberry (Sambucus nigra).\u00a0
\n<\/span>Thomas referenced another study which established that cyanogenic
\nglycosides in American Elderberry are lower than those found in the European
\nElderberry. The toxicity study only encompassed the edible berries, and did not
\ninclude the leaves, stems, and branches. Tested were ripe berries,
\nred\/under-ripe berries, green berries, and pedicels (tiny stems that attach
\nberries to the umbel). Thomas stated that they even had a student who
\npainstakingly separated skin, seeds, pulp, and juice of berries, so the
\nindividual parts could be tested for glycosides.\u00a0 <\/span>Using the levels of cyanogenic glycosides
\nfound in commercial apple juice as a benchmark, the study found that all parts
\nof the raw elderberry \u2013 green, red or ripe \u2013 contained lower levels of
\nglycosides than commercial apple juice.<\/b> \u00a0<\/span>The study also examined the levels of
\nbeta-glucosidase found in elderberries.\u00a0
\n<\/span>Cyanogenic glycosides in elderberries represent a potential for cyanide,
\nbut only convert to cyanide if reacted with beta-glucosidase. The study found
\nthere were insufficient quantities of beta-glucosidase to convert the
\nglucosides to cyanide.<\/span><\/p>\n

The study
\nconcluded<\/b> that the raw berries of the American Elderberry were as safe, if not
\nsafer, than commercial apple juice because 1) cyanogenic glycoside levels were
\nextremely low, and 2) insufficient quantities of beta-glucosidase were present
\nto convert any glycosides to cyanide.
<\/span>\"Free<\/p>\n

The good news is
\nthat it doesn’t matter if we know the exact levels of glycosides in elderberry.\u00a0 <\/span>What matters is that we know that cyanide
\nevaporates at a temperature of a little over 78\u00b0F (26\u00b0C). <\/span><\/p>\n

I found a pretty
\ncomprehensive study of the effects of heating on cyanogenic glycosides, which
\nwas informative, and reassuring.\u00a0 <\/span>In the
\nstudy, bitter apricot seed was boiled in water for 15 minutes, resulting in a
\n98% reduction in glycosides.\u00a0 <\/span>Bamboo
\nshoots were down 91% after 15 minutes of boiling, and no detectable traces were
\nfound after 60 minutes of boiling.\u00a0
\n<\/span>Cassava boiled for 20 minutes was down by 97%, and only trace glycosides
\nwere found after 35 minutes.\u00a0 <\/span>Flax seed
\nwas dry heated for 15 minutes, resulting in only a 10% reduction in
\nglycosides.\u00a0 <\/span>The study referenced
\nprevious studies of dry heating which resulted in only 16-18% reductions, and
\nconcluded that dry-heating did not reduce cyanide content effectively. <\/span><\/p>\n

I\u2019d like to add
\none little side note, not related to toxicity, but relevant to heating
\nelderberries.\u00a0 <\/span>There are a few studies
\nwhich have examined the effects of heating elderberry.\u00a0 <\/span>One such study found \u201c<\/span>short-time heat treatment reduces
\npotential allergy-related risks deriving from elderberry consumption without
\nseriously affecting its properties as an antioxidant and free-radical scavenging
\nfood.\u201d\u00a0 <\/span>Another study indicates gentle
\nheating may render the polyphenols in elderberry more bioavailable, but this
\nparticular aspect is still controversial, and needs additional study.<\/span><\/p>\n

Taking all of
\nthis information into consideration, my personal conclusion is that
\nelderberries are as safe to consume as apples, with or without heating. Care
\nshould be taken to remove leaves, stems and branches, and a short 15 minute
\ngentle simmer shouldn\u2019t adversely affect the beneficial properties of the
\nberries. While not the tastiest raw berries I\u2019ve sampled, when checking my
\nbushes this afternoon, I didn\u2019t hesitate to pop a handful of elderberries into
\nmy mouth.<\/span><\/p>\n

<\/p>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"

New Information on Elderberry Toxicity from the November\/December 2019 issue – The Essential Herbalby Rebekah Bailey Writing this particular article proved to be one of my more interesting writing experiences.\u00a0 I had completed and submitted it, only to have a series of events unfold in the following couple of days which required Tina and me […]<\/p>\n","protected":false},"author":1,"featured_media":326392,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11764],"tags":[2912,6594,65559],"dealstore":[],"offerexpiration":[],"class_list":["post-326391","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-alternative-medicine","tag-elderberry","tag-information","tag-toxicity"],"yoast_head":"\nNew Information on Elderberry Toxicity - Som2ny Network<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fivemor.com\/?p=326391\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Information on Elderberry Toxicity - 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