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Caffeine is addictive.<\/a>Caffeine causes insomnia.<\/a>Caffeine has no health benefits.<\/a>Caffeine is full of health benefits. Caffeine is harmful for women trying to get pregnant.<\/a>When you\u2019re pregnant, you shouldn\u2019t drink coffee. It\u2019s fine to drink coffee when pregnant.\u00a0<\/p>\n \u00a0<\/p>\n We\u2019ve heard it all before.\u00a0<\/p>\n \u00a0<\/p>\n There is a lot of conflicting information out there about caffeine and its health consequences, especially for pregnant women, because there are a lot of conflicting scientific studies about the topic. So, when you Google this topic, the advice is often confusing.<\/p>\n \u00a0<\/p>\n We have decided to explore this topic, giving you\u2014our Amara<\/a> readers\u2014a well-researched deep dive into this much-talked-about stimulant.\u00a0<\/p>\n \u00a0<\/p>\n \u00a0<\/p>\n Caffeine is a\u00a0naturally occurring central nervous system stimulant found in many foods, beverages, dietary supplements, and drugs. (To get technical, it\u2019s an alkaloid from the methylxanthines family.) It\u2019s known to improve vigilance, attention, and reaction time, particularly in sleep-deprived individuals. Many of us know it best in the form of coffee, the most common way that caffeine enters the human food chain. (Energy drinks, a rising market since the 1980s, is another common way, at least in the U.S., that caffeine enters our systems.)\u00a0<\/p>\n \u00a0<\/p>\n But did you know that caffeine has other uses as well? For instance, it occurs naturally in certain plant leaves, seeds, and fruits, where it serves as an herbicide, insect repellant, and even attractant for pollination.\u00a0<\/p>\n \u00a0<\/p>\n It is also employed to treat very ill and premature newborns afflicted with apnea (temporary cessation of breathing). Other uses include as an adjuvant (an aid) in pain therapy. In the sports world, caffeine is known to improve endurance and muscle strength.<\/p>\n \u00a0<\/p>\n There are almost no age, gender, geographical, or cultural barriers to the consumption of caffeine: it is the most widely consumed psychoactive substance in history. Its availability is nearly unlimited, and in Europe it is not subject to state regulation. In the U.S., the FDA has regulated caffeine as an ingredient in food since 1958, when the Food Additives Amendment to the Federal Food, Drug, and Cosmetic Act was enacted. This is why, on Coca-Cola bottles and cans, for instance, you see how much caffeine is contained.\u00a0<\/p>\n \u00a0<\/p>\n For reference, coffee contains about 85 to 110 mg of caffeine per cup, tea about 40-50 mg\/cup, soda beverages 30 to 45 mg\/serving, cocoa about 5 mg\/cup, and chocolate 25 mg\/small bar.<\/p>\n \u00a0 \u00a0<\/p>\n Caffeine consumption in adults has many recognized benefits, including helping to prevent:\u00a0<\/p>\n -neurological diseases (e.g., Parkinson\u2019s and Alzheimer\u2019s diseases)<\/p>\n -cardiovascular diseases (e.g., coronary heart disease and stroke)<\/p>\n -certain cancers (e.g., prostate cancer, melanoma, liver cancer, and breast cancer)<\/p>\n -liver diseases (e.g., liver fibrosis and liver cirrhosis)<\/p>\n -type 2 diabetes<\/p>\n \u00a0<\/p>\n The caveat to this is that the FDA\u2014and many other agencies across the world (including in Europe, Canada, New Zealand, India, and Australia\u2014recommend healthy, non-pregnant adults restrict their caffeine intake to around 400 milligrams a day (~4-5 cups of coffee) to take advantage of its health benefits while avoiding negative ones. The FDA has not set a level for children, but the American Academy of Pediatrics discourages the consumption of caffeine and other stimulants by children and adolescents.<\/p>\n \u00a0<\/p>\n \u00a0<\/p>\n Many experts conclude that caffeine is safe within a typical dose amount. But overconsumption of caffeine can cause or contribute to\u00a0insomnia, nervousness, restlessness, nausea, headache, a feeling of unhappiness, increased heart rate, and other cardiovascular effects like elevated blood pressure. And a sudden decrease in\u00a0caffeine\u00a0may cause withdrawal symptoms such as fatigue, irritability, headache, and difficulty focusing on tasks. Indeed, habitual consumption leads to physical dependence, which is why when we suddenly stop drinking coffee, we experience behavioral and physiological effects.\u00a0<\/p>\n \u00a0<\/p>\n But only in very high doses can caffeine be really unsafe, to the point of fatality, but\u2014again\u2014this is rare. The FDA estimates that toxic effects like seizures can be observed after the rapid consumption of around 1,200 milligrams of caffeine (~12 cups!), or 0.15 tablespoons of pure caffeine.\u00a0<\/p>\n \u00a0<\/p>\n Pure caffeine, often found in dietary supplements, should be treated with extreme caution. It often comes in highly concentrated powder or liquid form, where just one teaspoon of powder can contain the same amount of caffeine as 28 cups of coffee, and a half cup of liquid concentrate contains the equivalent of more than 20 cups of coffee. Yikes! And what makes it scarier is that dietary supplements are often marketed in bulk packaging with up to thousands of servings per container, requiring the consumer to measure out what they think is a safe serving. The FDA, importantly, does not regulate them in the same way as medications.<\/p>\n But again, aside from these supplements, most of us get caffeine from a few cups of coffee which\u2014again\u2014many experts say, \u201cdon\u2019t worry about.\u201d<\/p>\n \u00a0 \u00a0<\/p>\n If you are pregnant, trying to conceive, or have been pregnant, you\u2019ve probably heard that caffeine consumption during pregnancy increases certain risks, namely the risk of pregnancy failure and gestational complications like low birth weight. In fact, in 1980, the FDA issued a warning advising pregnant women to restrict or abstain from the drug following studies (using rodents, mind you) that showed harmful effects to fetuses.<\/p>\n \u00a0<\/p>\n And yet, many pregnant women today consume caffeine. In recent studies from the U.S., anywhere from 70 to 82% of pregnant women polled reported consuming caffeine daily (and for comparison\u2019s sake, studies show it\u2019s around 91% in France).\u00a0<\/p>\n \u00a0<\/p>\n \u00a0<\/p>\n Well, for one, updated studies (post-1980) have reassured many medical experts: many (not all, but many) currently maintain that under a certain amount, caffeine consumption during pregnancy is most likely safe for the fetus.<\/p>\n \u00a0<\/p>\n The American College of Obstetricians and Gynecologists advises that pregnant women may safely consume up to 200 mg of caffeine per day (~2 cups of moderate-strength coffee), and the same advice is contained in the Dietary Guidelines for Americans. Similarly, the European Food Safety Authority states that maternal consumption of caffeine up to 200 mg per day does \u201cnot give rise to safety concerns for the fetus\u201d, and the UK National Health Service advises pregnant women to \u201climit\u201d daily intake to 200mg. The Swedish National Food Agency recommends an intake of less than 300\u00a0mg caffeine per day during pregnancy. And the World Health Organization likewise says that daily caffeine consumption below 200\u2013300 mg is a safe dosage for pregnant women.\u00a0<\/p>\n \u00a0<\/p>\n Furthermore, many medical researchers and practitioners note that the effects of caffeine on pregnancy outcomes vary greatly from individual to individual because there is wide variation in both how sensitive people are to the effects of caffeine and how fast they metabolize it. Furthermore, scientists point to how genetics, epigenetics (how your behaviors and environment can affect your genes), and environmental conditions can predispose certain individuals to higher sensitivities to caffeine while pregnant.\u00a0<\/p>\n \u00a0<\/p>\n Basically, when it comes to caffeine dosage recommendations, it\u2019s more nuanced than we previously understood.<\/p>\n \u00a0 \u00a0<\/p>\n In adults, caffeine is metabolized by enzymes in the liver (specifically, cytochrome P450 enzymes). As a result, over 90% of ingested caffeine in adults get metabolized before it reaches the kidneys.\u00a0<\/p>\n \u00a0<\/p>\n But fetuses lack this enzyme system.* And when the mom consumes caffeine, it crosses the placenta, exposing the fetus to concentrations of the drug similar to levels in the mother.\u00a0<\/p>\n \u00a0<\/p>\n (*In fact, this enzyme system is primitive even in infancy. In newborns, more than 80% of caffeine consumed (via their moms\u2018 breastmilk) passes through their kidneys unmetabolized. As a result, infants of caffeine-consuming mothers can experience caffeine withdrawal symptoms much like adults, including disturbed sleep, vomiting, tremors, and irregular heartbeat and respiration.)<\/p>\n \u00a0<\/p>\n As women advance through pregnancy, their \u201cclearance of caffeine\u201c\u2014how much and quickly they metabolize\u2014changes. In the first trimester, women can process caffeine much like they do when not pregnant. But their ability to do so\u2014that rate\u2014slows to one-half and then to about one-third during the second and third trimesters. As part of this, caffeine\u2019s half-life (how long it lasts in our systems\/bodies) increases in the first trimester from the usual adult rate of about 2.5-5 hours to about 15-18 hours by the 38th week of pregnancy.<\/p>\n \u00a0<\/p>\n For fetal health, exposure to caffeine can lead to \u201cvasoconstriction in the uteroplacental circulation\u201c\u2014meaning, it can cause blood vessels involved maternal blood flow to narrow, constricting the exchange of oxygen and nutrients to the baby. This can, in turn, affect the baby\u2018s growth and development, leading to possible outcomes of preterm birth, low birth weight, and miscarriage. Studies show that children born small for their age have an increased risk of cardiovascular disease later in life and a higher chance of impaired neurodevelopment during childhood.\u00a0<\/p>\n \u00a0<\/p>\n You might be asking yourself: if this ^ is true, why did my doctor say I could drink 200 mg of coffee a day while pregnant?<\/p>\n \u00a0<\/p>\n Many medical researchers and practitioners distinguish between high, moderate, and low intakes of caffeine when they advise about it\u2014a low to moderate dose being 200-300 mg or less.\u00a0<\/p>\n \u00a0<\/p>\n Scientists established this threshold from recent studies. One of the largest ongoing cohorts\u2014where 64,000 full-term pregnant women in Norway were recruited from 1998 to 2008\u2014showed that low to moderate caffeine consumption during pregnancy was not associated with any persistent adverse effects concerning the child\u2019s neurodevelopment up to 8\u00a0years of age.\u00a0<\/p>\n \u00a0<\/p>\n So many experts consider caffeine a significant risk for pregnancy only when moms-to-be are consuming large quantities of caffeine. In the language of coffee, a high intake could be considered ~3\u00b75 to 7 cups of coffee per day and a very high caffeine intake as \u22657 cups of coffee per day.<\/p>\n \u00a0<\/p>\n At these levels, some studies suggest a significant increase in the risk of childhood acute lymphoblastic leukemia. Similarly, some studies from the U.S., Netherlands, Ireland, and Norway correlate high dosages of prenatal caffeine to babies with higher body mass indexes, total body fat, and liver fat, contributing to childhood obesity.<\/p>\n \u00a0<\/p>\n Of course, here\u2019s the tricky part of medical science: it\u2019s an ever-evolving project. To this point, some researchers disagree on what exactly constitutes a high intake of caffeine, versus a moderate or low dose. Even more muddying, some researchers have concluded that any caffeine intake is harmful to fetuses.\u00a0<\/p>\n \u00a0<\/p>\n One meta-analysis, for instance, showed that the risk of pregnancy loss increases by 19% for each increase of 150 mg\/day of caffeine, and 8% for each increase of 2 cups of coffee per day. Another meta-analysis found that 100 mg of caffeine per day during pregnancy was associated with a 14-26% increased risk of pregnancy loss. Additionally, the analysis found that pregnant women who ingested 2 or more cups of coffee per day before pregnancy had a higher risk of bleeding in early pregnancy.<\/p>\n \u00a0<\/p>\n Other studies, though, have concluded low and moderate amounts of caffeine have no effect. And others claim that low and moderate amounts of caffeine are beneficial for pregnancy, reducing the risk of gestational diabetes, as one example.<\/p>\n \u00a0<\/p>\n Confusing!<\/p>\n \u00a0<\/p>\n One 2015 study underscored this ambiguity, concluding: \u201cThere is insufficient evidence to confirm or refute the effectiveness of caffeine avoidance on birthweight or other pregnancy outcomes. There is a need to conduct high-quality, double-blinded RCTs [randomly controlled trials] to determine whether caffeine has any effect on pregnancy outcomes.\u201d<\/p>\n \u00a0<\/p>\n Many medical experts would agree with this premise: we need more studies. And that\u2019s because each existing study\u2014while useful\u2014is limited. One study alone cannot answer all our questions, in part because it\u2019s difficult to isolate caffeine intake and pregnancy as the only 2 variables in a woman\u2019s and her baby\u2019s health. What about the mom\u2019s age? Race\/ethnicity? Genetic health and predispositions? Her body mass index? Does she smoke? What\u2019s her personality and stress level? Other consumption habits? Kinds of caffeine consumed (coffee, soft drinks, etc.)? Exact amounts of caffeine consumed?\u00a0<\/p>\n \u00a0<\/p>\n This last question is particularly thorny. Many substances contain caffeine\u2014dark chocolate, for instance\u2014so when we tally up how much caffeine we *think* we had in a day, accurate estimates are hard to come by. On top of that, one person\u2019s\u2014or one company\u2019s\u2014cup of coffee might be stronger than the next. There\u2019s a lot of variability even in commonly recognized sources of caffeine.\u00a0<\/p>\n \u00a0<\/p>\n To this point, while high maternal caffeine intakes are more consistently associated with a higher risk of pregnancy loss and other negative results, the outcomes for moderate and low caffeine use have been mixed\u2014due to difficulties in measuring caffeine intakes and differences in participants and studies. That said, it\u2019s worth reiterating that ACOG and other expert bodies currently advise that up to 200 mg\/day is most likely safe.<\/p>\n \u00a0<\/p>\n \u00a0<\/p>\n We at Amara<\/a> care about caffeine consumption and pregnancy because we care about women\u2019s and babies\u2019 health\u2014which is why we\u2019re in the business of nutrient-dense baby and toddler food. Amara\u2019s baby blends<\/a> and toddler snacks<\/a> have no additives, are 100% non-GMO and organic, and are made from only a few\u2014very real, very transparent\u2014ingredients. Only the best for our babies.\u00a0<\/p>\n \u00a0<\/p>\n ***<\/p>\n Article researched by: \u00a0<\/p>\n References:<\/p>\n \u00a0<\/p>\nFirst things first: what is caffeine?<\/h2>\n
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<\/p>\nWhat are its health benefits?<\/h2>\n
What are the negatives of caffeine?<\/h2>\n
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<\/p>\nOK\u2014but what about pregnant women?<\/h3>\n
So what gives?<\/h3>\n
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<\/p>\nLet\u2019s dig into this more: what exactly does caffeine do to a pregnant woman and her baby?<\/h3>\n
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\u00a0<\/p>\nSo what should you do if you are pregnant, trying-to-conceive, or breastfeeding?<\/h3>\n
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Amara’s Chief Nutritionist: Sonia A. Schiess, PhD in Nutrition, specialized in the introduction of solids and liquids to infants. Sonia’s passion started when she was studying nutrition and dietetics in university, completing a post degree in Human Nutrition. Later on, she completed her PhD as a nutritionist, with a focus on introducing food in the first year of a baby’s life. Her wide experience gives her a unique perspective, drawing from her time in clinics, hospitals, independent consulting and university research. She’s authored several papers including “Introduction of complementary feeding”; “Introduction of potentially allergenic foods in the infant’s diet during the first year of life” and “Intake of energy providing liquids during the first year of life” in five European countries. The combination of Sonia’s science and our chef’s magic ensures every Amara product is not only optimized for your baby’s health but is delicious as well.<\/p>\n