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Targeting epidermal TRPV3 calcium channel alleviates psoriasis-like inflammation in vitro and in vivo
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Psoriasis is a chronic type 17 inflammatory skin disorder driven by a reciprocal crosstalk between immune cells and epidermal keratinocytes (KCs). In the ...

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Gastric Organoid-Based Ectopic and Orthotopic In Vivo CRISPR Screening for Tumor Suppressors in Gastric Cancer
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Transplantation of genetically modified organoids into the mouse stomach generates tumors that recapitulate the mutation spectrum and major risk factors, ...

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